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RECRUITING
NCT06626022
PHASE3

Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.

Sponsor: University of Alberta

View on ClinicalTrials.gov

Summary

The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland. Participants will be randomized into two groups to compare the imaging results of the current standard of care MRI and the new microUS. The study is looking to identify the most effective imaging modality to help guide whether you progress to have a prostate biopsy.

Official title: A Phase 3, Multicenter, International, Non-inferiority, Randomized Clinical Trial Comparing Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging (MUSIC-Screen)

Key Details

Gender

MALE

Age Range

50 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

1284

Start Date

2025-05-08

Completion Date

2029-11-30

Last Updated

2026-04-06

Healthy Volunteers

Yes

Interventions

DEVICE

MRI

Standard prostate mpMRI.

DEVICE

ExactVu

microUltrasound

Locations (6)

University of California, Los Angeles (UCLA)

Los Angeles, California, United States

University of Alberta

Edmonton, Alberta, Canada

University of British Columbia

Vancouver, British Columbia, Canada

CIUSSS du Nord-de-l'Île-de-Montréal

Montréal, Quebec, Canada

CH de Martigues

Martigues, France

Urologia Clinica Bilbao

Bilbao, Spain