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Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
Sponsor: University of Alberta
Summary
The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland. Participants will be randomized into two groups to compare the imaging results of the current standard of care MRI and the new microUS. The study is looking to identify the most effective imaging modality to help guide whether you progress to have a prostate biopsy.
Official title: A Phase 3, Multicenter, International, Non-inferiority, Randomized Clinical Trial Comparing Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging (MUSIC-Screen)
Key Details
Gender
MALE
Age Range
50 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
1284
Start Date
2025-05-08
Completion Date
2029-11-30
Last Updated
2026-04-06
Healthy Volunteers
Yes
Conditions
Interventions
MRI
Standard prostate mpMRI.
ExactVu
microUltrasound
Locations (6)
University of California, Los Angeles (UCLA)
Los Angeles, California, United States
University of Alberta
Edmonton, Alberta, Canada
University of British Columbia
Vancouver, British Columbia, Canada
CIUSSS du Nord-de-l'Île-de-Montréal
Montréal, Quebec, Canada
CH de Martigues
Martigues, France
Urologia Clinica Bilbao
Bilbao, Spain