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Efficacy of Lipid-Lowering Therapy Based on Apolipoprotein B Versus LDL-Cholesterol Levels in Patients Undergoing Percutaneous Coronary Intervention
Sponsor: University Medical Center Ho Chi Minh City (UMC)
Summary
This multicenter randomized trial is designed to assess the efficacy of lipid-lowering therapy in patients undergoing percutaneous coronary intervention, comparing an Apolipoprotein B-targeted approach with a Low-Density Lipoprotein Cholesterol (LDL-C)-targeted approach. The primary outcomes are to evaluate the proportion of patients achieving lipid-lowering treatment goals at the 1-year follow-up between the two treatment strategies: Apolipoprotein B-based therapy versus LDL-C-based therapy.
Official title: Efficacy of Lipid-Lowering Therapy Based on Apolipoprotein B Versus LDL-Cholesterol Levels in Patients Undergoing Percutaneous Coronary Intervention: a Multicenter, Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1448
Start Date
2025-01-01
Completion Date
2029-01-01
Last Updated
2024-10-16
Healthy Volunteers
No
Conditions
Interventions
ApoB-guided-LLT
Patients in this group will receive treatment regimens adjusted accordingly to meet the Apolipoprotein B targets
LDL-C-guided-LLT
Patients in this group will receive treatment regimens adjusted accordingly to meet the LDL-C targets.
Locations (1)
University Medical Center Ho Chi Minh City
Ho Chi Minh City, Vietnam