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ENROLLING BY INVITATION
NCT06628193
NA

Study of Low-intensity Focused Ultrasound Effects on Human Memory

Sponsor: Virginia Polytechnic Institute and State University

View on ClinicalTrials.gov

Summary

This research project is examining the effects of noninvasive brain stimulation on human memory. This study will help to better understand noninvasive brain stimulation techniques that may have the potential to aid in memory dysfunction. Subjects will undergo a magnetic resonance imaging (MRI) and a computed tomography (CT) scan, to take pictures of their brain and skull. They will receive noninvasive brain stimulation using low-intensity focused ultrasound (LIFU) sound waves, to temporarily change brain activity. Their brain signals (MRI or EEG) will be monitored to measure changes in their brain signals. Their heart rate, blood pressure, respiratory rate, eye movement and skin moisture will be monitored as well. They will complete neuropsychological batteries and memory tasks. They will complete questionnaires.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2024-11-18

Completion Date

2027-05

Last Updated

2026-03-31

Healthy Volunteers

Yes

Conditions

Interventions

DEVICE

Low intensity focused ultrasound

low-intensity focused ultrasound for neuromodulation applied to the head.

DEVICE

Sham (No Treatment)

Sham LIFU application

Locations (1)

Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States