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Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
Sponsor: University of Michigan
Summary
The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse and reduce patient harm. Findings from this study will lay the groundwork for broad implementation of D-THIO and serve as a model for deprescribing inappropriate medications for other endocrine conditions and conditions with biochemical monitoring.
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
900
Start Date
2024-12-02
Completion Date
2029-04
Last Updated
2026-02-13
Healthy Volunteers
No
Conditions
Interventions
D-THIO (Deprescribing Thyroid Hormone In Older Adults)
D-THIO consists of evidence-based pharmaceutical opinion letters to providers advising deprescribing for their patients 65 years and older with thyroid hormone overtreatment/misuse and EMPOWER ("Eliminating Medications through Patient Ownership of End Results") brochures to their patients.
Enhanced usual care
American Thyroid Association \[ATA\] provider guidelines, ATA patient brochure
Locations (3)
University of California San Francisco
San Francisco, California, United States
University of Michigan
Ann Arbor, Michigan, United States
Henry Ford Health System
Detroit, Michigan, United States