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Bronchoscopic Lung Volume Reduction in Management of Localized Emphysema
Sponsor: Mansoura University Hospital
Summary
Emphysema is a progressive phenotype of chronic Obstructive Pulmonary Disease (COPD), poses a significant global health burden characterized by irreversible lung parenchymal destruction and airspace enlargement. In recent years, bronchoscopic lung volume reduction (BLVR) has considerable interest as a minimally invasive approach to reducing hyperinflation and improving lung function in patients with emphysema. BLVR techniques aim to achieve lung volume reduction by occluding or ablating emphysematous lung tissue through endobronchial delivery of various agents. Many techniques are available for BLVR as coil, endo-bronchial valve, and biological as thrombin, autologous blood and chemicals as silver nitrate solution.
Official title: Efficacy and Safety of 0.5% w/v Nano- Silver Nitrate Versus Silver Nitrate Solution for Bronchoscopic Lung Volume Reduction in Management of Localized Emphysema: Prospective Interventional Randomized Controlled Clinical Trial
Key Details
Gender
All
Age Range
40 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-10-01
Completion Date
2026-03-01
Last Updated
2025-05-29
Healthy Volunteers
No
Conditions
Interventions
Silver Nitrate
bronchoscopic lung volume reduction in management of localized emphysema
Nano-silver nitrate
bronchoscopic lung volume reduction in management of localized emphysema
Bronchoscopic lung volume reduction
bronchoscopic lung volume reduction in management of localized emphysema
Locations (1)
Mohamed AbdElmoniem
Al Mansurah, Egypt