Clinical Research Directory

Inclusion Criteria: 1. Male or female healthy volunteers. 2. Age 18 to 55 years. 3. BMI between 18.5-30 kg/m2. 4. Weight between 50-100 kg. 5. Healthy as determined by the investigator or designee based on pre-investigational medical and surgical history, and health examination at enrollment. 6. Women of childbearing potential (defined as all women who are not surgically sterile or postmenopausal for at least 1 year prior to enrollment) must have a negative urine pregnancy test at enrollment and at visit 2 and must agree to use a medically acceptable contraception from enrollment until clinical investigation completion. 7. No current drug usage defined as a negative urine drug test at enrollment and at visit 2. 8. Able to use Previct Drugs after initial training (defined as successfully performing a test set after trying maximum three times per measurement). 9. Voluntarily agrees to participate and has duly singed the Informed Consent Form. Exclusion Criteria: 1. Participating in another clinical investigation which may affect the clinical investigation outcome according to clinical judgement. 2. Previously participated in the KCClin01 investigation. 3. Pregnant or lactating. 4. Blind and/or deaf. 5. Clinically abnormal ECG, according to the investigator. QTcF time above 450 ms at enrollment. 6. Resting heart rate above 90 BPM. 7. Current or recent history of alcohol misuse assessed by AUDIT where ≥6 points for women or ≥8 points for men indicates a potential misuse. 8. Current or history of psychiatric disorder or drug misuse assessed by M.I.N.I where the outcome will be based on clinical judgement. 9. Any disease or condition that may influence pupillary reflexes based on clinical judgement. 10. Undergone eye surgery that may influence pupillary reflexes based on clinical judgement. 11. Ongoing treatment with medications which may interfere with eye measurements based on clinical judgement. 12. Ongoing treatment with medications which may interfere with any of the medicinal products to be used. 13. History or presence of allergy or serious reaction to the medicinal products to be used. 14. History or presence of cardiovascular disease, e.g., arteriosclerosis, hypertension, or cor pulmonale. 15. History or presence of sleep-related breath disorder. 16. History or presence of gastrointestinal disease, e.g., paralytic ileus, acute abdomen, delayed gastric emptying, or chronic constipation. 17. History or presence of pulmonary disease, e.g., acute pulmonary insufficiency, severe respiratory depression with hypoxia, chronic obstructive lung disease, or bronchial asthma. 18. History or presence of autoimmune neuromuscular disease, e.g., myasthenia gravis. 19. Not able to read or understand the local language. 20. Any other condition that as judged by the investigator may make the follow-up or investigation inappropriate.