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RECRUITING
NCT06631976
NA

Conservative Treatment in Patients With Supraspinatus Tendon Injury.

Sponsor: Medical University of Lodz

View on ClinicalTrials.gov

Summary

Rotator cuff injuries are a major cause of severe pain, often significantly impacting patients\' sleep quality. For patients waiting for surgery or those not eligible for operative treatment, conservative treatment is recommended. In cases of minor injuries, physiotherapy is as effective as surgical intervention. The aim of this study is: (1) to compare the speed, effectiveness, and durability of four implemented interventions in improving sleep quality, pain, and shoulder function, (2) to select the most optimal form of conservative treatment for patients with shoulder pain affecting sleep quality, and (3) to evaluate the expression of brain-derived neurotrophic factor (BDNF) and proBDNF (precursor) at the mRNA protein level before the planned intervention (T0), 1 month (T1), 3 months (T3), and 6 months (T6) after intervention. The study results can assist physicians and physiotherapists in providing patients with therapy that not only relieves pain and improves function but also augments sleep quality, an aspect often overlooked in the literature yet greatly impacting patients\' quality of life.

Official title: Comparison of Conservative Treatment Methods for Sleep Disorders, Pain, and Shoulder Function in Patients With Supraspinatus Tendon Injury.

Key Details

Gender

All

Age Range

40 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-06-04

Completion Date

2026-09

Last Updated

2025-12-10

Healthy Volunteers

No

Interventions

DRUG

1ml of Depo-Medrol® injection

1ml of methylprednisolone acetate (40mg/ml) injection into subacromial bursa.

OTHER

Rehabilitation

Rehabilitation

DRUG

Nerve block with 4ml of 2% lidocaine

Nerve block with 4ml of 2% lidocaine around the suprascapular nerve

DRUG

Tropocells® PRP injection

Tropocells® PRP injection. Patients will have an 11ml venous blood sample taken. After centrifugation, the obtained preparation will be administered to the patients intratendinously.

Locations (1)

Medical University of Lodz

Lodz, Łódź Voivodeship, Poland