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Conservative Treatment in Patients With Supraspinatus Tendon Injury.
Sponsor: Medical University of Lodz
Summary
Rotator cuff injuries are a major cause of severe pain, often significantly impacting patients\' sleep quality. For patients waiting for surgery or those not eligible for operative treatment, conservative treatment is recommended. In cases of minor injuries, physiotherapy is as effective as surgical intervention. The aim of this study is: (1) to compare the speed, effectiveness, and durability of four implemented interventions in improving sleep quality, pain, and shoulder function, (2) to select the most optimal form of conservative treatment for patients with shoulder pain affecting sleep quality, and (3) to evaluate the expression of brain-derived neurotrophic factor (BDNF) and proBDNF (precursor) at the mRNA protein level before the planned intervention (T0), 1 month (T1), 3 months (T3), and 6 months (T6) after intervention. The study results can assist physicians and physiotherapists in providing patients with therapy that not only relieves pain and improves function but also augments sleep quality, an aspect often overlooked in the literature yet greatly impacting patients\' quality of life.
Official title: Comparison of Conservative Treatment Methods for Sleep Disorders, Pain, and Shoulder Function in Patients With Supraspinatus Tendon Injury.
Key Details
Gender
All
Age Range
40 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-06-04
Completion Date
2026-09
Last Updated
2025-12-10
Healthy Volunteers
No
Conditions
Interventions
1ml of Depo-Medrol® injection
1ml of methylprednisolone acetate (40mg/ml) injection into subacromial bursa.
Rehabilitation
Rehabilitation
Nerve block with 4ml of 2% lidocaine
Nerve block with 4ml of 2% lidocaine around the suprascapular nerve
Tropocells® PRP injection
Tropocells® PRP injection. Patients will have an 11ml venous blood sample taken. After centrifugation, the obtained preparation will be administered to the patients intratendinously.
Locations (1)
Medical University of Lodz
Lodz, Łódź Voivodeship, Poland