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RECRUITING
NCT06632379
PHASE4

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

Sponsor: Ohio State University

View on ClinicalTrials.gov

Summary

The objective is to conduct a double-blinded randomized controlled trial of atorvastatin vs. placebo among postpartum individuals with hypertensive disorders of pregnancy, to improve cardiovascular risk score postpartum. For this, 76 individuals with hypertensive disorders of pregnancy (HDP) will be randomized to atorvastatin 10mg or placebo, which will be started in the postpartum period after cessation of breast feeding and continued for 3 months.

Official title: AtorvaStatin Postpartum and Reduction of Cardiovascular risK (SPARK): A Randomized Placebo-controlled Trial of Atorvastatin Postpartum for Reduction of Cardiovascular Risk

Key Details

Gender

FEMALE

Age Range

20 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

76

Start Date

2025-10-03

Completion Date

2026-12-15

Last Updated

2025-10-20

Healthy Volunteers

No

Interventions

DRUG

Atorvastatin 10 mg

Participants will be assigned to 10 mg Atorvastatin

DRUG

Placebo

Participants will be assigned to identical appearing placebo

Locations (1)

The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine

Columbus, Ohio, United States