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AtorvaStatin Postpartum and Reduction of Cardiovascular risK
Sponsor: Ohio State University
Summary
The objective is to conduct a double-blinded randomized controlled trial of atorvastatin vs. placebo among postpartum individuals with hypertensive disorders of pregnancy, to improve cardiovascular risk score postpartum. For this, 76 individuals with hypertensive disorders of pregnancy (HDP) will be randomized to atorvastatin 10mg or placebo, which will be started in the postpartum period after cessation of breast feeding and continued for 3 months.
Official title: AtorvaStatin Postpartum and Reduction of Cardiovascular risK (SPARK): A Randomized Placebo-controlled Trial of Atorvastatin Postpartum for Reduction of Cardiovascular Risk
Key Details
Gender
FEMALE
Age Range
20 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
76
Start Date
2025-10-03
Completion Date
2026-12-15
Last Updated
2025-10-20
Healthy Volunteers
No
Interventions
Atorvastatin 10 mg
Participants will be assigned to 10 mg Atorvastatin
Placebo
Participants will be assigned to identical appearing placebo
Locations (1)
The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine
Columbus, Ohio, United States