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Utility of Analyzing Atrial Signal Electrograms in Patients with Atrial Fibrillation Using Next-Generation Ensite X Software: a Prospective Study
Sponsor: Taipei Veterans General Hospital, Taiwan
Summary
A single-center clinical trial on the analysis of intracardiac atrial electrogram mapping before and after ablation with the HD Grid Mapping Catheter and Ensite X Software, as a prospective study.
Key Details
Gender
All
Age Range
20 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2024-10-01
Completion Date
2027-06-30
Last Updated
2024-10-17
Healthy Volunteers
No
Conditions
Interventions
Catheter ablation
The catheter ablation strategy is the same as the current treatment approach in patients with AF, according to the consensus of catheter ablation of AF. All procedures will be performed under local sedation or general anesthesia depending on the operator, and each patient will undergo an electrophysiological study and substrate mapping in the fasting state with adequate pre-ablation anticoagulation and transesophageal echocardiography to rule out LA thrombus. All antiarrhythmic drugs except amiodarone will be discontinued for at least 5 half-lives before the procedure. Step I: Substrate mapping before ablation, Step II: Pulmonary vein isolation (PVI), Step III: Post-ablation mapping in SR immediately after ablation, Step IV: Inducibility after ablation, Step V: Remmaping 30 minutes after ablation
Locations (1)
Taipei Veterans General Hospital
Taipei, Taiwan