Clinical Research Directory

Inclusion Criteria: * meet the clinical diagnosis of Long COVID by the World Health Organization (WHO), with no neuropsychiatric symptoms 1 year before infection with Covid-19, and continue to have at least one neuropsychiatric symptom for 2 months after SARS-CoV-2 turned negative 3 months above; * aged 12 to 80 years; * willing and able to consent, and complete all assessment and study procedures Exclusion Criteria: * patients with a history of chronic neuropsychiatric symptoms; * cardiovascular diseases pre-existing to the Covid-19 episode such as arrhythmia, heart failure, myocardial infarction, and patients with cardiac pacemakers; * documented pre-existing history of psychiatric illness, including substance abuse; * suicidal tendencies (attempted suicide in the 12 months before the study); * any chronic or remote neurological disorder (i.e. stroke, head trauma, epilepsy, tumor); * those who participated in other clinical trials within one month; * pregnant or lactating female patients; * have surgery within two months before the study or will have a scheduled surgery during the study; * acute brain injury or acute encephalopathy from another etiology than Covid-19 (e.g., sepsis, liver or renal failure, alcohol or drug withdrawal, drug toxicity); * open-heart cardiac surgery or cardiac arrest during the last 6 months; * patients who received acupuncture treatment 1 month before the start of the study; * patients who were unable to complete the assessment during screening due to severe mental, cognitive, or emotional impairment