Clinical Research Directory

Inclusion Criteria: * Over 18 years of age * Presence of teeth in the second sextant (edentulous section of a single tooth with the presence of adjacent teeth on both sides of the absence is accepted). * No sites with attachment loss (AL) \> 3 mm in the area to be treated (second sextant). * Present full mouth plaque index (Ainamo and Bay, 1975) \<15%. * Have bleeding on probing (BoP; Ainamo \& Bay 1975) \<15%. Exclusion Criteria: * pregnancy or lactation * patients who smoke * patients under treatment with antimicrobials and anti-inflammatory drugs in the last 2 months or with medications associated with changes in the gingival tissue (antiepileptics, calcium channel blockers, etc.) * subjects with systemic conditions that alter the normal presentation of the gingival tissue (hereditary gingival fibromatosis) or those diagnosed with uncontrolled diabetes mellitus * patients with severe dental malposition and/or presence of dental implants in the area to be treated * use of orthodontic appliances * all those who present a disability or mental disorders that make it difficult for the patient to understand or follow them during the study period. study period.