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A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women
Sponsor: Ohio State University Comprehensive Cancer Center
Summary
This clinical trial tests whether a new dietary pattern that consists of foods that lower the blood insulin response can reduce breast cancer risk in high-risk women. In a large group of patients, this new dietary pattern was associated with reduced risk of multiple cancers and reduced risk of long-term weight gain. Parts of this new dietary pattern are quite different from typical dietary recommendations, and much education is needed. Overall, compared to the typical American diet, this new dietary pattern is moderately low in total fat and saturated fat, low in protein from animal foods but high in protein from plant sources, high in fruits and vegetables, high in whole grains, and high in dietary fiber. We will determine if a low-insulinemic dietary pattern intervention is feasible and effective in reducing breast cancer risk in high-risk women.
Key Details
Gender
FEMALE
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-10-03
Completion Date
2026-03-31
Last Updated
2025-10-16
Healthy Volunteers
Yes
Conditions
Interventions
Biospecimen Collection
Undergo blood sample collection
Dietary Intervention
Receive the Low-EDIH dietary pattern intervention
Medical Device Usage and Evaluation
Wear an activity tracker
Motivational Interviewing
Undergo motivational interviews
Nutritional Assessment
Participate in nutrition counseling
Questionnaire Administration
Ancillary studies
Locations (1)
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States