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RECRUITING
NCT06635291

Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE)

Sponsor: IRCCS Eugenio Medea

View on ClinicalTrials.gov

Summary

The present study aims to investigate the clinical evolution of children with severe ABI and DoC both by using the traditional behavioral scales, namely the CRS-R, CRS-P and CNCS, and by trying to establish whether it is possible to identify any clinical markers of Emergency (E-Markers). E-Markers are behaviors that indicate a content of consciousness irrespective of the processes investigated by behavioral scales, thus they could be combined with the items of these scales to improve the diagnosis. A particular focus will be given to the identification of specific E-Markers for children aged less than 12 months, for which the CRS-P scale cannot be used. In this case, the E-markers will be compared with the specific developmental stages of newborns, giving great importance to motor abilities.

Official title: Improving the Diagnostic Accuracy of Children with Disorders of Consciousness in the REhabilitation Process (IDeAl DesiRE)

Key Details

Gender

All

Age Range

2 Months - 25 Years

Study Type

OBSERVATIONAL

Enrollment

113

Start Date

2024-05-20

Completion Date

2026-12-31

Last Updated

2024-12-16

Healthy Volunteers

No

Locations (1)

Scientific Institute, IRCCS E. Medea

Bosisio Parini, Lecco, Italy