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Impact Of Kidney Failure On The Regulation Of Humoral Response To Vaccination
Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Summary
The aim of this observational study is to determine if and how kidney failure affects the development of protective immune responses following vaccination in patients on chronic dialysis. Researchers will compare the effectiveness of the influenza vaccine in inducing protective antibodies between hemodialysis patients and subjects without chronic kidney disease. Participants will: * Be enrolled at the time of influenza vaccination * Visit the clinic at 7, 14, 30, 60, and 120 days after vaccination * Be asked to provide relevant clinical information and a blood sample at each visit
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
146
Start Date
2024-10-16
Completion Date
2026-07
Last Updated
2026-03-30
Healthy Volunteers
Yes
Interventions
Influenza vaccination
Single-dose
SARS-CoV-2 vaccine
Single-dose
Locations (3)
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
ASST Santi Paolo e Carlo
Milan, Italy
ASST Fatebenefratelli Sacco
Milan, Italy