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RECRUITING
NCT06635525

Impact Of Kidney Failure On The Regulation Of Humoral Response To Vaccination

Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

View on ClinicalTrials.gov

Summary

The aim of this observational study is to determine if and how kidney failure affects the development of protective immune responses following vaccination in patients on chronic dialysis. Researchers will compare the effectiveness of the influenza vaccine in inducing protective antibodies between hemodialysis patients and subjects without chronic kidney disease. Participants will: * Be enrolled at the time of influenza vaccination * Visit the clinic at 7, 14, 30, 60, and 120 days after vaccination * Be asked to provide relevant clinical information and a blood sample at each visit

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

OBSERVATIONAL

Enrollment

146

Start Date

2024-10-16

Completion Date

2026-07

Last Updated

2026-03-30

Healthy Volunteers

Yes

Interventions

BIOLOGICAL

Influenza vaccination

Single-dose

BIOLOGICAL

SARS-CoV-2 vaccine

Single-dose

Locations (3)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

ASST Santi Paolo e Carlo

Milan, Italy

ASST Fatebenefratelli Sacco

Milan, Italy