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Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain
Sponsor: University of Chicago
Summary
Post-operative pain and lower urinary tract symptoms are common following ureteroscopy in the treatment of stone disease. The use of bupivacaine as a topical pain medication is used routinely for other urologic procedures, however, to date there are no studies that have rigorously investigated the effect of instilling bupivacaine in the bladder following ureteroscopy. This is a randomized study that will investigate the effect of instilling bupivacaine in the bladder following routine ureteroscopy, laser lithotripsy and ureteral stenting in the treatment of stone disease. Compared to a placebo of Normal Saline, our study hypothesizes that administration of topical bupivacaine in the bladder will decrease post-operative pain and lower urinary tract symptoms while improving quality of life in the early post-operative period.
Official title: Double-Blind Randomized Placebo Controlled Trial of Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
116
Start Date
2025-03-26
Completion Date
2029-10
Last Updated
2025-11-10
Healthy Volunteers
Yes
Conditions
Interventions
Bupivacaine
The dose plan is to use 50 ml of 0.25% bupivacaine which corresponds with a total dose of 125mg.
Normal saline
Placebo of 50 ml of Normal Saline
Locations (1)
The University of Chicago Medical Center
Chicago, Illinois, United States