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RECRUITING
NCT06636578
PHASE4

Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block

Sponsor: Fayoum University

View on ClinicalTrials.gov

Summary

In 2012 Blanco et al. \[1\] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries. PECS block includes PECS I and PECS II (modified PECS I) interfascial blocks. Since that time, PECS block has been used successfully with good results for a wide variety of surgeries on the chest wall such as radical mastectomies, breast-conserving surgeries, breast implant placement, automated implantable cardioverter-defibrillator (AICD)/pacemaker placement, intercostal drainage tube placement, and rib fractures. In this study, the investigators hypothesized that adding dexmedetomidine as an adjuvant to ropivacaine can result in the prolongation of the duration of anesthesia with improvement of the quality of postoperative analgesia of bilateral PECS block for patients undergoing cardiac surgery via midline sternotomy compared with using only plain ropivacaine.

Official title: Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block for Fast Tracking and Postoperative Analgesia in Open Heart Surgery Through Midline Sternotomy. A Randomized Clinical Trial

Key Details

Gender

All

Age Range

20 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2024-10-10

Completion Date

2025-01-08

Last Updated

2024-10-15

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

dexmedetomidine

will receive 30 ml of 0.25% of ropivacaine + dexmedetomidine 0.5 μg/kg for each side.

DRUG

ropivacaine

will receive 30 ml of 0.25% of plain ropivacaine for each side.

DRUG

fentanyl

will not receive any regional anesthesia and only will receive I.V. fentanyl 1μg/kg/hr.

Locations (2)

Fayoum University Hospital

Al Fayyum, Egypt

Mohamed Hamed

Al Fayyum, Egypt