Clinical Research Directory
Browse clinical research sites, groups, and studies.
High - Flow Nasal Cannula Versus Conventional Nasal Cannula During Endobronchial Ultrasound Procedure
Sponsor: The University Clinic of Pulmonary and Allergic Diseases Golnik
Summary
EBUS bronchoscopy is performed in most centers under local anesthesia and moderate sedation. Both the bronchoscopy itself and the sedation can lead to decreased ventilation and a drop in oxygen saturation in the body. Typically, oxygen is administered during the procedure via a nasal cannula at a flow rate of 6l/min. The aim of the study is to compare a new method - a nasal cannula with high flow - to the standard cannula. The primary objective is to demonstrate that the new method is more effective at preventing desaturation during the procedure. Patients will be randomized into two groups before bronchoscopy and monitored. The bronchoscopy will be performed in the same way for both groups. The only difference between the groups will be in the method of oxygen administration during EBUS bronchoscopy.
Official title: HFNC Versus Conventional Nasal Cannula During EBUS Procedure: a Randomised Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-03-01
Completion Date
2024-11-01
Last Updated
2024-10-15
Healthy Volunteers
No
Conditions
Interventions
High - flow nasal cannula
High flow nasal cannula (HFNC), a device first introduced in neonates and pediatric care, is currently used in a wide range of indications in adult respiratory and critical care medicine (5-7). It is a relatively new method in bronchoscopy with several notable theoretical advantages over low flow oxygen via conventional nasal cannula (CNC): * High flow up to 60 liters per minute ensures a more stable FiO2 and better matches the increased patient's inspiratory flow * High flow generates a small positive expiratory airway pressure (up to 5 cm H2O) which could stabilize the upper airways during sedation and have a beneficial effect in the lower airways * High flow reduces dead space in the upper airways and increases alveolar ventilation.
Standard nasal cannula
Standard method for supplementing oxygen during EBUS bronchoscopy
Locations (4)
University Hospital Centre Zagreb - Jordanovac
Zagreb, City of Zagreb, Croatia
National and Kapodistrian University of Athens
Athens, Athens, Greece
Clinica Universitaria de Pneumologia, Hospital de Santa Maria
Lisbon, Lisbon District, Portugal
University Clinic Golnik
Golnik, Golnik, Slovenia