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Study in Patients With Breast Cancer Leptomeningeal Metastasis
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Summary
Traditional clinical trials in patients with breast cancer leptomeningeal disease (LMD) are challenging as patients often have a rapidly progressive course and prognosis is poor, making meeting standard eligibility difficult. Furthermore, there is limited information about the biology of LMD. The investigators thus propose a study that is as inclusive as possible, which will allow the investigators to collect biospecimens and clinical outcomes to learn more about LMD biology, but still potentially provide benefit for patients, by providing patients rapid diagnostics and multi-disciplinary treatment recommendations.
Official title: A Translational Observational Biorepository and Management Study in Patients With Breast Cancer Leptomeningeal Metastasis: The BioLept Study
Key Details
Gender
All
Age Range
18 Weeks - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-11-25
Completion Date
2028-12
Last Updated
2025-11-28
Healthy Volunteers
No
Locations (2)
Sibley Memorial Hospital
Washington D.C., District of Columbia, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States