Clinical Research Directory

Inclusion Criteria for HZ: * Meets HZ diagnostic criteria; * Female, aged between 50 and 70 years; * Disease duration ≤7 days, with no prior antiviral, analgesic, or other treatments; * Herpetic lesions limited to the trunk, within 1 to 3 dermatomes; * Willing to participate in the trial and has signed the informed consent form. Inclusion Criteria for HC: * No history of HZ or major cardiovascular, respiratory, digestive, urinary, hematologic, endocrine, or neurological diseases; * Age-matched female HC volunteers for the HZ group; * Clear consciousness and ability to communicate normally; * Fully understands the study protocol, demonstrates good compliance, and is willing to cooperate with the study; * Has signed a written informed consent form. Exclusion Criteria: * Special types of herpes zoster, including ophthalmic, otic, visceral, meningeal herpes zoster, and zoster sine herpete; * Women who are planning to conceive, pregnant, or breastfeeding; * Patients with severe primary diseases of the circulatory, respiratory, or endocrine systems, or systemic failure; * Patients with bleeding tendencies; * Use of corticosteroids or immunosuppressants within the past month.