Clinical Research Directory

Inclusion Criteria: * 1\. Patients with clinical symptoms consistent with localized scleroderma (LoSCAT score can be used to assist in diagnosis). 2\. Diagnosed with secondary alopecia caused by localized scleroderma. 3. A history of hair loss in the affected area for more than 6 months, with an adequate supply of donor hair. 4\. The disease is inactive and has been in a stationary phase for over a year (patients have no ongoing or intermittent hair loss accompanied by local pain, itching, or burning; scalp biopsy indicates no inflammatory cell infiltration, hair follicle orifices have disappeared, and hair follicles are replaced by connective tissue). 5\. The general condition is stable, and the patient can tolerate anesthesia and surgery. 6\. BMI is greater than or equal to 17. 7. Age between 18 and 59. 8. The subject and their family are willing and able to comply with postoperative care and follow-up requirements. 9\. The subject and their family have given informed consent and have signed the informed consent form. Exclusion Criteria: 1. Hair loss area exceeds one-third of the scalp. 2. Infection of the scalp soft tissue. 3. Suffering from psychiatric disorders, hematologic diseases, immune deficiencies, abnormalities in liver or kidney function, severe hypertension, severe diabetes, and other contraindications for surgery. 4. Women who are pregnant or breastfeeding. 5. BMI is less than 17, making it impossible to obtain sufficient fat. 6. Received new vasodilator or immunosuppressive drug treatment within the past 3 months. 7. Applied topical ointments to the surgical area within the past 2 weeks. 8. Positive for HIV, HBV, HCV, HTLV-1 or -2, or syphilis. 9. Patients with a history of tumor formation in the last 5 years. 10. Patients with a prednisolone intake greater than 10 mg/day. Patients deemed unsuitable for participation in this trial by the investigator's judgment.