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Liposomal Bupivacaine and Bupivacaine for TTMPB in Median Sternotomy
Sponsor: Tongji Hospital
Summary
In light of the ongoing controversy surrounding the efficacy of bupivacaine liposomes, our study was designed to investigate, for the first time, the differential postoperative analgesic effects between bupivacaine liposomes combined with bupivacaine hydrochloride and bupivacaine hydrochloride alone in transverse thoracic muscle plane block treatment. The aim is to provide evidence-based medical guidance for drug selection in regional block local anesthesia.
Official title: Liposomal Bupivacaine and Bupivacaine Alone Transverse Thoracic Muscle Plane Blocks in Median Sternotomy: a Prospective, Single-blind, Randomized Controlled Study
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
38
Start Date
2024-10-24
Completion Date
2026-10-12
Last Updated
2024-10-28
Healthy Volunteers
No
Conditions
Interventions
Transverse thoracic muscle plane block (TTMPB) using liposomal bupivacaine and bupivacaine mixture
Liposomal bupivacaine and bupivacaine mixture were used for transverse thoracic muscle plane block (TTMPB) in experimental group.
Transverse thoracic muscle plane block (TTMPB) using bupivacaine hydrochloride
Bupivacaine hydrochloride was used for transverse thoracic muscle plane block (TTMPB) in active control group.
Locations (1)
Tianzhu Liu
Wuhan, Hubei, China