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Comparison of Different Electroporation Systems in the Ablation Treatment of Atrial Fibrillation
Sponsor: University Hospital Dubrava
Summary
The participant is invited to participate in a clinical study comparing three different techniques for treating atrial fibrillation (AF) called electroporation systems. Atrial fibrillation is an irregular heartbeat that can cause complications if left untreated. The goal of this study is to determine which electroporation system is the most effective and safest for treating AF. These systems work by using electrical energy to disrupt abnormal heart tissue, helping to restore a normal heart rhythm.
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-10-15
Completion Date
2025-05-01
Last Updated
2025-04-01
Healthy Volunteers
Yes
Conditions
Interventions
Electroporation
Unlike traditional thermal ablation techniques such as radiofrequency (RF) and cryoablation, the electroporation systems used in this study rely on pulsed electric fields (PEF) to selectively target and ablate cardiac tissue. This non-thermal mechanism reduces the risk of collateral damage to nearby structures, such as the esophagus, phrenic nerve, and coronary arteries.
Locations (2)
Clinical Hospital Dubrava, Department of Cardiology
Zagreb, City of Zagreb, Croatia
UHDubrava
Zagreb, Croatia