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RECRUITING
NCT06647459

Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation

Sponsor: Vanderbilt University Medical Center

View on ClinicalTrials.gov

Summary

To use programmed ventricular stimulation at the time of AF ablation to define the prevalence and mechanism of inducible ventricular tachycardia (VT); pace-mapping to define the site of origin of ventricular arrhythmias; and voltage mapping to define low voltage scar substrate in the basal LV in patients with pathogenic TTN variants compared to genotype-negative controls.

Official title: Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2023-12-13

Completion Date

2027-01-01

Last Updated

2026-02-10

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

EP Study

To use programmed ventricular stimulation at the time of AF ablation to define the prevalence and mechanism of inducible ventricular tachycardia (VT); pace-mapping to define the site of origin of ventricular arrhythmias; and voltage mapping to define low voltage scar substrate in the basal LV in patients with pathogenic TTN variants compared to genotype-negative controls.

Locations (1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States