Clinical Research Directory
Browse clinical research sites, groups, and studies.
Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy
Sponsor: University Medical Center Groningen
Summary
This study will be a multicentre prospective cohort study on TH-substitution after thyroid hormone withdrawal preceding radioiodine treatment.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2026-09-01
Completion Date
2028-12-31
Last Updated
2026-02-10
Healthy Volunteers
No
Interventions
Euthyrox (levothyroxine)
Euthyrox (levothyroxine sodium tablets; L-T4) is a thyromimetic synthetic drug identical to T4. Patients will recieve levothyroxine (euthyrox) in a dose of 2 μg × kg body weight / day.
Cytomel (liothyronine)
Cytomel (liothyronine sodium tablets; L-T3) is a thyromimetic synthetic drug identical to T3. The patients in this cohort recieve L-T4+L-T3 combination therapy. The L-T4 dose will be 2 μg × kg body weight / day, equal to the dose in the other interventional arm. L-T3 will be added twice daily from the first day of combination treatment, in dosages gradually decreasing from 25 ug 2/day to 5 ug 2/day over a time span of 3 weeks after which L-T3 is stopped.
Locations (2)
University Medical Center Groningen (UMCG)
Groningen, Provincie Groningen, Netherlands
Radboud University Nijmegen
Nijmegen, Netherlands