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Pelvis Adaptive Radiotherapy (ART)
Sponsor: Royal North Shore Hospital
Summary
Pelvis Adaptive radiotherapy (ART) is a two phase study looking at using adaptive radiotherapy to help reduce toxicity for cancer patients having radiotherapy in the pelvic region. Adaptive radiotherapy is a new technology that provides the ability to account for daily changes in anatomy. Adaptive radiotherapy also provides a foundation for which radiotherapy margins might be safely reduced. Phase 1 of this study is looking to see if a radiation therapist centred adaptive workflow can be implemented. If phase 1 of this study is safe and feasible, the study will proceed to phase 2. Phase 2 of the study looks at using adaptive technology to reduce radiation treatment margins. The primary aim of this study is to see whether margin reduced treatment using adaptive radiotherapy can reduce side effects for patients with cancer in the pelvic area.
Official title: Pelvis Adaptive Radiation Therapy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
280
Start Date
2025-10-09
Completion Date
2031-11-30
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
Adaptive radiotherapy +/- margin reduction
Radiotherapy using adaptive technology to recontour and re-plan daily as required. Reductions in the PTV margin will also be introduced in the second phase of this study.
Image guided radiotherapy
Standard radiation treatment used in the department of radiation oncology for cancer in pelvic area
Locations (1)
Northern Sydney Local Health District
St Leonards, New South Wales, Australia