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COMPLETED
NCT06650930
EARLY_PHASE1

Pharmacokinetics of Oral Calcium Carbonate in Parturients

Sponsor: Stanford University

View on ClinicalTrials.gov

Summary

This study investigates the time course of change in calcium in the blood after a pregnant subject takes an oral dose of calcium carbonate (commonly marketed as "Tums"). Midway through the trial, with IRB permission, the oral calcium formulation was switched to calcium citrate to test whether this, better-absorbed formulation might prove more effective in increasing serum calcium. This information is important for trials investigating whether oral calcium can reduce postpartum hemorrhage, bleeding after delivery.

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2025-01-23

Completion Date

2025-12-03

Last Updated

2026-08-12

Healthy Volunteers

No

Interventions

DRUG

Oral calcium carbonate

Participants receive a single, open-label dose of oral calcium carbonate 1200mg

DRUG

Oral calcium citrate

Participants receive a single oral dose of calcium citrate 1250mg

Locations (1)

Stanford Children's Health, Lucile Packard Children's Hospital

Stanford, California, United States