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Pharmacokinetics of Oral Calcium Carbonate in Parturients
Sponsor: Stanford University
Summary
This study investigates the time course of change in calcium in the blood after a pregnant subject takes an oral dose of calcium carbonate (commonly marketed as "Tums"). Midway through the trial, with IRB permission, the oral calcium formulation was switched to calcium citrate to test whether this, better-absorbed formulation might prove more effective in increasing serum calcium. This information is important for trials investigating whether oral calcium can reduce postpartum hemorrhage, bleeding after delivery.
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-01-23
Completion Date
2025-12-03
Last Updated
2026-08-12
Healthy Volunteers
No
Interventions
Oral calcium carbonate
Participants receive a single, open-label dose of oral calcium carbonate 1200mg
Oral calcium citrate
Participants receive a single oral dose of calcium citrate 1250mg
Locations (1)
Stanford Children's Health, Lucile Packard Children's Hospital
Stanford, California, United States