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AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
Sponsor: Technical University of Munich
Summary
The investigators analyze the impact of exercise and ablation in patients with symptomatic short-persistent atrial fibrillation (Afib) and heart failure with preserved ejection fraction (HFpEF). It is hypothesized that the combination of ablation and exercise better improves peak oxygen consumption (VO2peak) through improvement of peripheral (exercise training) and central (ablation) adaptations. Exercise intervention will contain a 12-week combined, video-based, supervised, endurance, resistance and respiratory training.
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2026-02-01
Completion Date
2027-06-30
Last Updated
2025-12-26
Healthy Volunteers
No
Interventions
Exercise training
exercise intervention will consist of supervised, home-based, combined training with elements of endurance, resistance and respiratory training
Locations (1)
Department of Medicine, Division of Prevention and Sports Medicine TU Munich
Munich, Germany