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Does Ethyl Chloride Spray Work?
Sponsor: University of Chicago
Summary
A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.
Official title: Does "Freeze Spray" Work? Evaluating the Efficacy of Ethyl Chloride Usage Prior to Orthopaedic Injections
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-04-01
Completion Date
2028-12-01
Last Updated
2025-10-16
Healthy Volunteers
No
Interventions
Ethyl Chloride
Topical anesthetic that rapidly cools the skin and underlying tissues
Cold Saline Spray
placebo application of cold saline spray
Locations (1)
University of Chicago
Chicago, Illinois, United States