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Immunogenomic Analyses of Pediatric Catatonia
Sponsor: Rady Pediatric Genomics & Systems Medicine Institute
Summary
Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 40 children and adolescents who are admitted to Rady Children's Hospital San Diego with a catatonia diagnosis. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve the ability to identify the cause of catatonia and impact care. The investigator also hopes to identify new genetic and/or autoimmune causes of catatonia that may inform new treatment for future patients.
Key Details
Gender
All
Age Range
0 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2024-12-01
Completion Date
2030-09-01
Last Updated
2024-11-14
Healthy Volunteers
No
Conditions
Interventions
Genetic: Genomic sequencing and molecular diagnostic results, if any.
Genomic sequencing results may be used for diagnosis and treatment of participants.
Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)
Whole Proteome programmable phage display immunoprecipitation sequencing will be used to diagnose known and novel autoantibodies.