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Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients
Sponsor: Our Lady of the Lake Hospital
Summary
EGFR gene mutations are some of the most commonly occurring mutations in non-small cell lung cancer. Investigators have developed a DNA instability model that estimates a risk score to assess the likelihood of an individual acquiring a cancer-linked mutation. The aim of this study is to collect blood from both those diagnosed with EGFR positive lung cancer and healthy individuals, evaluate their gene sequence surrounding the EGFR landscape and use the cancer positive and healthy sequences to validate the risk assessment model, which may one day be used to provide insight on susceptibility of getting EGFR positive lung cancer or potentially other cancer types.
Key Details
Gender
FEMALE
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2025-01-01
Completion Date
2025-12-31
Last Updated
2025-03-20
Healthy Volunteers
Yes
Interventions
blood draw
A 10ml Blood sample will be taken and used to sequence the EGFR gene and surrounding DNA.
Gene sequencing
Subjects will have their DNA sequenced within and around the EGFR gene.
Locations (1)
Our Lady of the Lake Regional Medical Center
Baton Rouge, Louisiana, United States