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ENROLLING BY INVITATION
NCT06660680
PHASE3

The Effect of Methylene Blue Infiltrating Injection on Anal Pain After Milligan-Morgan Surgery: A Randomized Controlled Clinical Study

Sponsor: The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine

View on ClinicalTrials.gov

Summary

A variety of analgesic strategies are available following mixed hemorrhoids surgery, including pharmacological interventions (7), acupuncture, moxibustion, and electroacupuncture . Medications such as opioid analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used but can be associated with side effects including nausea, vomiting, and gastrointestinal bleeding, with long-term use potentially leading to addiction (8). Complementary therapies require skilled administration and regular treatment sessions. Methylene blue (MB), a cationic thiazine dye extensively utilized as a biological stain and chemical indicator, has been increasingly recognized for its potential analgesic properties (9). In the present study, methylene blue infiltrating injection (MBI) was administered to treat anal pain resulting from Milligan-Morgan surgery, with the aim of assessing its analgesic efficacy and safety profile.

Official title: the Ethics Committee of the Second Hospital of Chinese Medicine

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2024-10-25

Completion Date

2025-10-01

Last Updated

2024-10-28

Healthy Volunteers

No

Interventions

DRUG

Methylene Blue

Received MBI treatment to their surgical incisions upon completion of surgery

Locations (1)

Second hospital affiliated Anhui University of Chinese Medicine

Hefei, Anhui, China