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Primary and Secondary Drug Resistance Mutations (DRMs) in HIV As a Risk Factor of Failure of ART, Including Two Drugs Based Regimens.
Sponsor: Medical University of Warsaw
Summary
The presence of drug resistance mutations (DRMs) in HIV plays an important role in ART effectiveness. Despite very good results of ART, there is constant concern about the emergence of HIV strains with DRMs, what may lead to virological suppression failure. The concerns grow especially among patients treated with two drugs based regimens, including long acting therapies in injections (LAI ART) or regimens used in preexposure prophylaxis (PreP).
Official title: Presence of HIV-1 DRMs As a Risk Factor of Failure of Two Drugs Based ART Regimens, Including LAI ART, in Cohorts of Primary and Secondary DRMs.
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2024-11-01
Completion Date
2024-12-30
Last Updated
2024-10-28
Healthy Volunteers
No
Conditions
Interventions
no intervention
no intervention
Locations (1)
Department of Infectious Diseases, Tropical Diseases and Hepatology, Medical University of Warsaw
Warsaw, Mazowia, Poland