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NOT YET RECRUITING
NCT06661356
NA

Peer-led Community-based PrEP Delivery Among Youth in Brazil

Sponsor: University of Alabama at Birmingham

View on ClinicalTrials.gov

Summary

The goal of this project is to conduct a series of studies to refine, test, and understand experiences with a peer-led community-based intervention in which youth will be integrated into health care teams and trained to deliver HIV pre-exposure prophylaxis (PrEP) to their peers. The study team will conduct a randomized trial to determine if peer delivery of PrEP to youth aged 15-24 in Brazil will increase PrEP uptake, persistence, and adherence compared to standard PrEP care provided in health facilities.

Official title: Determining the Impact of Peer-led Community-based PrEP Delivery Among Youth in Brazil: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

15 Years - 24 Years

Study Type

INTERVENTIONAL

Enrollment

1400

Start Date

2026-10

Completion Date

2029-08

Last Updated

2026-03-05

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

COMPrEP

Participants will be paired with peer lay workers and will meet with peer lay workers at private community location. They will discuss options for oral PrEP with peer lay workers and be provided provide daily oral PrEP or event-driven (2-1-1) PrEP. Participants will take part in rapid HIV testing at each visit. They will also meet with peer lay workers at private community location for follow-up at 1, 5, 9, and 13 months.

Locations (2)

Federal University of Bahia

Salvador, Estado de Bahia, Brazil

University of São Paulo

São Paulo, São Paulo, Brazil