Clinical Research Directory

Inclusion Criteria: * Age: 18 to 65 * Caustic, traumatic, anastomotic, post-operative, radiation-induced or post-endoscopic (mucosal resection, submucosal dissection) benign esophageal stricture refractory to endoscopic dilatation. * For women: effective contraception for the entire duration of the study (from signature of consent to end of follow-up) * Affiliated or beneficiary of a social security scheme. * Free written consent signed by the participant and the investigator. Exclusion Criteria: * Weight loss \> 10% of body weight over last 3 months * Stenosis \> 5 cm in length * Multiple strictures * Esophageal mouth stenosis * Anterior surgery close to the operative zone * Complete anterior omentectomy * Tumour stenosis or progressive tumour pathology * Non-stabilized psychiatric disorders * Participation in another interventional study * Pregnant or breast-feeding women * Women of childbearing age without effective contraceptive measures: All women of childbearing age must have a negative pregnancy test prior to treatment and must agree to maintain highly effective contraception using contraceptive measures from the date of consent until 12 months due to the risks associated with anesthesia during endoscopy * Uncontrolled sepsis * Related to the transplant procedure * ASA score ≥ 3, * Severe respiratory insufficiency (FEV1 \< 1 L), * Decompensated hepatic cirrhosis or presence of esophageal varices, * Chronic renal insufficiency (creatinine \> 1.25 N), * Myocardial infarction less than 6 months old or progressive heart disease, * WHO general condition \> 2, * Weight loss \>20% not recovered after renutrition. * Contraindication to general anaesthesia, analgesics and antibiotics. * Conditions requiring long-term immunosuppressive or corticosteroid treatment. * Patients under curatorship or guardianship