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Vaginal Microbiome Research Consortium for Africa
Sponsor: University of Cape Town
Summary
1. To characterise vaginal microbial community dynamics (bacterial and fungal) from different geographies in Africa to understand the microbial diversity that occurs in women with stable L. crispatus-dominant versus unstable vaginal microbiota. 2. To identify vaginal communities associated with low levels of inflammation in women from different geographies in Africa 3. To examine prevalence and diversity of HPV types circulating in the different geographies and their interaction with the vaginal microbiota 4. To create a biobank of stored samples that can be used in future studies and for the isolation of regionally representative bacterial strains.
Official title: Vaginal Microbiome Research Consortium for Africa - Pilot
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2021-10-15
Completion Date
2026-10-31
Last Updated
2025-08-03
Healthy Volunteers
Yes
Conditions
Interventions
None - observational study only
No interventions, diagnostics tests for HIV, pregnancy, STIs and BV only
Locations (2)
KEMRI
Kisumu, Kisumu County, Kenya
Desmond Tutu Health Foundation
Cape Town, Western Cape, South Africa