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RECRUITING
NCT06662747

Vaginal Microbiome Research Consortium for Africa

Sponsor: University of Cape Town

View on ClinicalTrials.gov

Summary

1. To characterise vaginal microbial community dynamics (bacterial and fungal) from different geographies in Africa to understand the microbial diversity that occurs in women with stable L. crispatus-dominant versus unstable vaginal microbiota. 2. To identify vaginal communities associated with low levels of inflammation in women from different geographies in Africa 3. To examine prevalence and diversity of HPV types circulating in the different geographies and their interaction with the vaginal microbiota 4. To create a biobank of stored samples that can be used in future studies and for the isolation of regionally representative bacterial strains.

Official title: Vaginal Microbiome Research Consortium for Africa - Pilot

Key Details

Gender

FEMALE

Age Range

18 Years - 40 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2021-10-15

Completion Date

2026-10-31

Last Updated

2025-08-03

Healthy Volunteers

Yes

Conditions

Interventions

DIAGNOSTIC_TEST

None - observational study only

No interventions, diagnostics tests for HIV, pregnancy, STIs and BV only

Locations (2)

KEMRI

Kisumu, Kisumu County, Kenya

Desmond Tutu Health Foundation

Cape Town, Western Cape, South Africa