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ENROLLING BY INVITATION
NCT06665958
NA

Comparison of the Bioavailability of the Flavanol of Grape Extracts

Sponsor: University of Ulster

View on ClinicalTrials.gov

Summary

Polyphenols are a group of naturally occurring compounds found in cocoa, teas, and grape seed extracts (GSE) that have been linked to various health benefits. This study will provide a greater insight into the relationship between polyphenol consumption and health, and could be used to help with the development of functional food products and novel supplements. Although the advantages of a polyphenol-rich diet are well-established, the bioavailability of GSE (a source of polyphenols) in the context of human digestion and beneficial properties are poorly understood. The investigators will conduct an open-label, randomized, 4-way crossover design with the aim to explore the bioavailability of GSE-derived flavan-3-ols from GSE and their related microbial metabolites and advance understanding of the bioactive properties of flavan-3-ols contributing to the development of more effective dietary strategies and functional food products.

Official title: Comparison of the Bioavailability of the Flavanol of Grape Extracts Administered in Capsule or in Gummy: a 4-way Randomized Crossover Study in Healthy Participants

Key Details

Gender

MALE

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

25

Start Date

2024-10-28

Completion Date

2025-09-01

Last Updated

2024-10-30

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Polyphenol extract

Single dose

Locations (1)

Ulster University,Human Intervention Studies UnitColeraine, Co. Londonderry BT521SA

Coleraine, Co. Londonderry, United Kingdom