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Earlier Prime-BOOST Schedule to Improve MEasles Protection in High Burden Settings
Sponsor: University of Oxford
Summary
This is a phase IIb clinical trial investigating the non-inferiority of immune responses in children given two doses of measles vaccine at different timepoints. The study will randomise 450 children to 3 groups: group A will receive measles containing vaccine (MCV) at 6 and 12 months ; group B at 9 and 18 months; Group C at 6 and 18 months.
Key Details
Gender
All
Age Range
23 Weeks - 28 Weeks
Study Type
INTERVENTIONAL
Enrollment
450
Start Date
2023-11-15
Completion Date
2026-05-10
Last Updated
2024-10-31
Healthy Volunteers
Yes
Conditions
Interventions
Licenced Measles-Rubella vaccine
Licenced Measles-Rubella vaccine provided by the Ugandan EPI programme
Locations (1)
Makarere University - Johns Hopkins University Collaboration
Kampala, Uganda