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RECRUITING
NCT06667206
PHASE2

Earlier Prime-BOOST Schedule to Improve MEasles Protection in High Burden Settings

Sponsor: University of Oxford

View on ClinicalTrials.gov

Summary

This is a phase IIb clinical trial investigating the non-inferiority of immune responses in children given two doses of measles vaccine at different timepoints. The study will randomise 450 children to 3 groups: group A will receive measles containing vaccine (MCV) at 6 and 12 months ; group B at 9 and 18 months; Group C at 6 and 18 months.

Key Details

Gender

All

Age Range

23 Weeks - 28 Weeks

Study Type

INTERVENTIONAL

Enrollment

450

Start Date

2023-11-15

Completion Date

2026-05-10

Last Updated

2024-10-31

Healthy Volunteers

Yes

Conditions

Interventions

BIOLOGICAL

Licenced Measles-Rubella vaccine

Licenced Measles-Rubella vaccine provided by the Ugandan EPI programme

Locations (1)

Makarere University - Johns Hopkins University Collaboration

Kampala, Uganda