Clinical Research Directory

Inclusion Criteria: \- Patients from 20 - 60 years old: 1. Patients Diagnosed as type 2 diabetes since ≥6 months 2. Patients Diagnosed with CKD GIII - IV non-HD 3. Patients Diagnosed with Metabolic associated fatty liver disease Exclusion Criteria: * 1\. Type 1 diabetes or non-diabetic patients 2. BMI ≥40 kg/m2 3. Other causes of chronic liver disease (e.g., Hepatitis B virus, Hepatitis c virus, HIV, autoimmune disease, Wilson disease, drugs, alpha one antitrypsin deficiency). 4\. Patients use of drugs known to cause hepatic steatosis (e.g., amiodarone, valproate, tamoxifen, methotrexate, corticosteroids, contraceptive pills) 5. Detection of biliary duct obstruction based on imaging studies. 6. Patient with history of liver transplantation 7. liver cirrhosis (on basis of ultrasonography and MRI) or hepatocellular carcinoma (evidence on triphasic CT or MRI). 8\. Intolerance or allergy SGLT2-I or any other substance in the tablets. 9. Refused to consent to this study.