Clinical Research Directory
Browse clinical research sites, groups, and studies.
Dietary Factors and Rheumatoid Arthritis Risk in the UK Biobank
Sponsor: University of Leeds
Summary
Rheumatoid arthritis (RA) is the most common inflammatory arthritis, affecting around 1% of the UK population. It affects around 400,000 adults and is characterised by synovial inflammation, cartilage and bone damage that requires lifelong treatment and represents a significant burden for both the individual and society. Diet can affect inflammatory status and RA risk, with varying risks for men and women on specific diets. People with low to moderate consumption of alcohol may be at a lower risk of RA. Those who consume lower intakes of fruit and vegetables could be at a greater risk than those with adequate intakes. This research aims to better understand the role of diet in reducing RA risk in men and women in the United Kingdom. The research will use existing dietary and lifestyle data from the United Kingdom Biobank Study and hospital records of RA incidence.
Official title: The Associations Between Diet and Rheumatoid Arthritis Risk in the UK Biobank
Key Details
Gender
All
Age Range
40 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
500000
Start Date
2006-01-01
Completion Date
2029-12-31
Last Updated
2024-11-01
Healthy Volunteers
Yes
Conditions
Interventions
Dietary patterns
Dietary patterns such as regular meat-eater, occasional meat-eater, pescatarian, and vegetarian; Mediterranean diet.
Food groups and Nutrients
Dietary components, such as oily fish, dairy product, supplements, fibre, vitamin D supplements.
Alcohol intake
Frequency and intake of alcoholic beverages was measured by self-reporting the weekly frequency of different types of alcoholic beverages, e.g., the number of pints of beer/cider consumed per week and measures of spirits or liquors consumed per week were collected to assess consumption of beer/cider and spirits.
Vitamin D status
Serum 25(OH)D was measured once at baseline through a non-fasted blood draw during any season of the year.