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NOT YET RECRUITING
NCT06670209
PHASE1

A Phase I Clinical Study to Evaluate the Effect of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects

Sponsor: Gan and Lee Pharmaceuticals, USA

View on ClinicalTrials.gov

Summary

This is a single-center, open-label, fixed-sequence phase I clinical study to evaluate the effect of multiple subcutaneous injections of GZR18 Injection on the pharmacokinetics of multiple oral doses of metformin hydrochloride tablets.

Official title: A Phase I, Open-label, Fixed-sequence Study to Evaluate the Effect of Repeated Subcutaneous Injections of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects

Key Details

Gender

All

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

32

Start Date

2024-10-30

Completion Date

2025-03-19

Last Updated

2024-11-01

Healthy Volunteers

No

Conditions

Interventions

DRUG

GZR18 and metformin

GZR18: 3 mg-18 mg Metformin: 500 mg