Clinical Research Directory

Inclusion Criteria: * Patients \>18 years. * Patients requiring vertebroplasty for the fixation of symptomatic pathological fractures of the thoracic or lumbar vertebral body resulting from osteoporosis or tumor. * Symptomatic vertebral compression fracture(s) confirmed by MRI with bone marrow oedema on T2/STIR sequences. * Diagnosis of osteoporosis (clinically and confirmed on DXA with quantifiable BMD) or pathological fracture due to tumor * Patients with 1 or more vertebral compression fractures of the thoracic or lumbar spine Note: Patients with a current vertebral compression fracture who also have a previous history of vertebral compression fractures of the thoracic or lumbar spine may be included. Study Specific Inclusion Criterion • Signed informed consent Exclusion Criteria: * Infection * Vertebral body collapse to less than 1/3 (33%) of original height * Vertebral plana (\>90% vertebral body collapse) * Spinal stenosis (retro pulsed fragments). * Unstable spine warranting surgical stabilization * Prophylactic treatment of any vertebrae with vertebroplasty * Irreversible life threating bleeding disorders * End stage kidney disease * Drug dependence (IVDU) * Pregnancy Study Specific Exclusion Criterion: • Unable or unwilling to follow the standard of care prescribed follow-up visits