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Assessment of Reproductive Outcomes in Non-Male Factor Infertility Patients: Conventional in Vitro Fertilisation Versus Intracytoplasmic Sperm Injection
Sponsor: Maria Dolores Cuquerella Fernandez-Vazquez
Summary
The aim of this clinical trial is to evaluate the efficiency of two fertilization techniques used in Assisted Reproduction: conventional In Vitro fertilization (cIVF) and Intracytoplasmic Sperm Injection (ICSI), in terms of in-vitro and clinical results, in non-male infertility patients, comparing them in sibling oocytes. The main questions it aims to answer are: Does ICSI result in better fertilization rate, blastocyst rate or usable blastocyst rate? Does ICSI result in better pregnancy, clinical pregnancy and live birth rates? Researchers will compare cIVF to ICSI in sibling oocytes to assess if a technique offers better results. Participants undergoing an IVF/ICSI cycle will have their oocytes randomly divided in two groups: the oocytes from one group will be fertilized using cIVF and the oocytes from the other group using ICSI.
Official title: Assessment of Reproductive and Perinatal Outcomes According to the Fertilisation Technique in Non-Male Factor Infertility Patients: Conventional in Vitro Fertilisation Versus Intracytoplasmic Sperm Injection
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
128
Start Date
2022-01-01
Completion Date
2025-03-01
Last Updated
2024-11-14
Healthy Volunteers
No
Interventions
conventional in vitro fertilization
Fertilization via conventional In Vitro Fertilization
intracytoplasmic sperm injection (ICSI)
Fertilization via intracytoplasmic sperm injection
Locations (1)
Hospital Clinico San Carlos
Madrid, Madrid, Spain