Clinical Research Directory

Browse clinical research sites, groups, and studies.

Sites Groups Studies

Back to Studies

RECRUITING

NCT06671483

PHASE3

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

Sponsor: Takeda

View on ClinicalTrials.gov

Summary

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects the joints and skin in people who have psoriasis (PsO). The main aim of the study is to know how well zasocitinib (TAK-279) works in participants with active PsA who have not previously been treated with biologic disease-modifying antirheumatic drugs. The participants will be treated with either zasocitinib, active comparator, or placebo. Participants will be in the study for up to 60 weeks.

Official title: A Multi-Center, Randomized, Double-Blind, Placebo- and Active-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Zasocitinib (TAK-279) in Subjects With Active Psoriatic Arthritis Who Are Naïve to Biologic Disease-Modifying Antirheumatic Drugs (LATITUDE-PsA-3001)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1088

Start Date

2025-03-03

Completion Date

2028-01-28

Last Updated

2026-04-06

Healthy Volunteers

Conditions

Psoriatic Arthritis

Interventions

DRUG

Zasocitinib

Zasocitinib over-encapsulated tablets.

DRUG

Active Comparator

Active comparator capsule.

DRUG

Placebo

Zasocitinib or active comparator matching placebo.

Locations (189)

AARR- Chandler AZ

Chandler, Arizona, United States

Arizona Arthritis & Rheumatology Research, PLLC | Phoenix, AZ

Phoenix, Arizona, United States

Arizona Arthritis & Rheumatology Research, PLLC | Phoenix, AZ

Phoenix, Arizona, United States

Arizona Arthritis & Rheumatology Research, PLLC | Phoenix, AZ

Phoenix, Arizona, United States

First OC Dermatology Research Inc.

Fountain Valley, California, United States

Purushotham & Akther Kotha MD

La Mesa, California, United States

Triwest Research Associates LLC

La Mesa, California, United States

The Cohen Medical Centers

Thousand Oaks, California, United States

Foothill Arthritis Clinic

Tujunga, California, United States

Medvin Clinical Research

Whittier, California, United States

Denver Arthritis Clinic | Denver, CO

Denver, Colorado, United States

Arthritis & Rheumatic Disease Specialties (AARDS)

Aventura, Florida, United States

RASF- Clinical Research Center

Boca Raton, Florida, United States

Clinical Research of West Florida | Clearwater, FL

Clearwater, Florida, United States

GNP Research, LLC | Hollywood, FL

Cooper City, Florida, United States

Driven Research LLC

Coral Gables, Florida, United States

Tectum Medical Research

Davie, Florida, United States

Sweet Hope Research Specialty, Inc, d/b/a Neoclinical Research

Hialeah, Florida, United States

Bioresearch Partners

Miami, Florida, United States

HMD Research LLC

Orlando, Florida, United States

Millennium Research | Ormond Beach, FL

Ormond Beach, Florida, United States

IRIS Research and Development | Plantation, FL

Plantation, Florida, United States

Sarasota Arthritis Research Center

Sarasota, Florida, United States

West Broward Rheumatology Associates, Inc.

Tamarac, Florida, United States

Clinical Research of West Florida | Tampa, FL

Tampa, Florida, United States

Marietta Rheumatology Associates

Marietta, Georgia, United States

GSCP/CIS

Orland Park, Illinois, United States

Greater Chicago Specialty Physicians LLC/CIS

Schaumburg, Illinois, United States

Accurate Clinical Research, Inc. | Lake Charles

Lake Charles, Louisiana, United States

Klein & Associates, M.D., P.A.

Hagerstown, Maryland, United States

Henry Ford Health System-Rheumatology Department

Detroit, Michigan, United States

Michigan Rheumatology Group, P.C. - Grand Blanc Office

Grand Blanc, Michigan, United States

Ash Research Clinic - Howell

Howell, Michigan, United States

June DO, PC Private Practice - Dr. Justus Fiechtner

Lansing, Michigan, United States

Clinical Research Institute of Michigan

Saint Clair Shores, Michigan, United States

Saint Louis Rheumatology

St Louis, Missouri, United States

Albuquerque Center for Rheumatology PC

Albuquerque, New Mexico, United States

Santa Fe Rheumatology

Santa Fe, New Mexico, United States

NYU Langone Health | Joseph S. and Diane H. Steinberg Ambulatory Care Center - Rheumatology Department

Brooklyn, New York, United States

Accellacare of Hickory

Hickory, North Carolina, United States

University Hospitals | UH Cleveland Medical Center - Department of Medicine - Rheumatology Division

Cleveland, Ohio, United States

Paramount Medical Research & Consulting, LLC

Middleburg Heights, Ohio, United States

PA Regional Center for Arthritis and Osteoporosis Research

Wyomissing, Pennsylvania, United States

West Tennessee Research Institute

Jackson, Tennessee, United States

Accurate Clinical Research

Baytown, Texas, United States

Novel Research | Bellaire Location

Houston, Texas, United States

Novel Research | Bellaire Location

Houston, Texas, United States

Accurate Clinical Research

Houston, Texas, United States

Introscience Research | Northwest Houston Arthritis Center - Houston, TX

Houston, Texas, United States

West Texas Clinical Research

Lubbock, Texas, United States

Southwest Rheumatology Research, LLC | Mesquite, TX

Mesquite, Texas, United States

Clinical Investigations of Texas

Plano, Texas, United States

Arthritis Northwest, PLLC | Spokane, WA

Spokane, Washington, United States

Medical College of Wisconsin | Department of Medicine - Rheumatology Division

Milwaukee, Wisconsin, United States

Université Libre de Bruxelles

Anderlecht, Brussels Capital, Belgium

University Hospital Ghent

Ghent, Flanders, Belgium

ReumaClinic Genk

Genk, Limburg, Belgium

St Pierre Brussels

Brussels, Belgium

Centre Hospitalier Universitaire (CHU) de Liege - Domaine Universitaire du Sart Tilman

Liège, Belgium

Diagnostic Consultative Centre - Focus-5 - LZIP EOOD

Sofia, Sofia-Grad, Bulgaria

Military Medical Academy Multiprofile Hospital for Not Yet Recruiting Treatment - Sofia

Sofia, Sofia-Grad, Bulgaria

Centre of Rheumatology St. Irina

Sofia, Sofia-Grad, Bulgaria

Medical Center Medconsult Pleven OOD

Pleven, Bulgaria

AES Partner Site -Plovdiv

Plovdiv, Bulgaria

Medical Center Artmed OOD | Plovdiv, Bulgaria

Plovdiv, Bulgaria

Diagnostic- Consultative Center- 1- Ruse EOOD

Rousse, Bulgaria

Dr Stoyanka Vladeva IPSMP VBR | Stara Zagora, Bulgaria

Stara Zagora, Bulgaria

Medical Center Zara-Med EOOD

Stara Zagora, Bulgaria

El Centro de Estudios Reumatologicos (CER)

Providencia, Santiago Metropolitan, Chile

Clinica Dermacross S.A.

Santiago, Santiago Metropolitan, Chile

Centro de Estudios Clinicos

Santiago, Chile

CTR Estudios

Santiago, Chile

Centro Internacional de Estudios Clínicos

Santiago, Chile

Medicinski Centar Kuna and Peric

Zagreb, City of Zagreb, Croatia

Clinical Hospital Centre Osijek

Osijek, Croatia

Clinical Hospital Center Rijeka

Rijeka, Croatia

University Hospital Centre Split

Split, Croatia

General Hospital Zadar

Zadar, Croatia

Revmatologie s.r.o. | Brno, Czech Republic

Brno, Czech Rep, Czechia

L.K.N. Arthrocentrum, s.r.o. - Revmatologicka

Hlučín, Czech Rep, Czechia

Clintrial s.r.o. | Prague, Czech Republic

Prague, Czech Rep, Czechia

Praglandia | Prague, Czech Republic

Prague, Czech Rep, Czechia

MEDICAL Plus s.r.o.

Uherské Hradiště, Czech Rep, Czechia

CCR Ostrava

Ostrava, Moravskoslezský kraj, Czechia

Pv Medical Services

Zlín, NAP, Czechia

Revmatologicky ustav | Clinical Evaluation Department

Prague, Prague, Czechia

Pratia Pardubice a.s.

Pardubice, Czechia

Innomedica OU | Tallinn, Estonia

Tallinn, Harju, Estonia

Center for Clinical and Basic Research

Tallinn, Harju, Estonia

Clinical Research Centre | Tartu, Estonia

Tartu, Tartu, Estonia

North Estonia Medical Centre | Mustamae Building - Internal Medicine Clinic - Rheumatology Department

Tallinn, Estonia

MediTrials OÜ

Tartu, Estonia

Fachklinik Bad Bentheim

Bad Bentheim, Lower Saxony, Germany

Rheumzentrum Prof.Dr.med.Gunther Neeck

Bad Doberan, Mecklenburg-Vorpommern, Germany

Rheumazentrum Ratingen-Studienambulanz

Ratingen, North Rhine-Westphalia, Germany

Universitaetsklinikum Leipzig AoeR

Leipzig, Saxony, Germany

Rheumatologische Schwerpunktpraxis | Berlin, Germany

Berlin, Germany

Städtisches Klinikum Dresden

Dresden, Germany

MVZ Rheumatologie und Autoimmunmedizin Hamburg GmbH - Hamburg

Hamburg, Germany

Medicover MVZ München Ost

München, Germany

Porcika Klinika

Hódmezővásárhely, Csongrad-Csanad, Hungary

Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont

Szeged, Csongrad-Csanad, Hungary

CMed Rehabilitacios es Diagnosztikai Kozpont

Székesfehérvár, Fejér, Hungary

Qualiclinic | Budapest, Hungary

Budapest, Hungary

Fejer Varmegyei Szent Gyorgy Egyetemi Oktató Korhaz | Rheumatology Department - Arthritis Center

Székesfehérvár, Hungary

Vital Medical Center Medical Center and Dental Center | Reumatologia - Veszprem, Hungary

Veszprém, Hungary

Assuta Ashdod Medical Center

Ashdod, Southern District, Israel

Barzilai Medical Center | Rheumatology Department

Ashkelon, Israel

Rambam Health Care Campus

Haifa, Israel

Galilee Medical Center | Rheumatology Unit

Nahariya, Israel

The Chaim Sheba Medical Center - The Zabludowicz Center for Autoimmune Diseases

Ramat Gan, Israel

Tel Aviv Sourasky Medical Center

Tel Aviv, Israel

Azienda Ospedaliero-Universitaria delle Marche; SOD Clinica Medica

Torrette, Ancona, Italy

Fondazione PTV Policlinico Tor Vergata

Rome, Lazio, Italy

Policlinico Agostino Gemelli, UOC Reumatology

Rome, Lazio, Italy

ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO

Milan, Lombardy, Italy

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele

Milan, Lombardy, Italy

IRCCS Istituto Clinico Humanitas

Rozzano, Milano, Italy

Azienda Ospedale Università Padova

Padova, Veneto, Italy

Azienda Ospedaliera Universitaria Careggi

Florence, Italy

Azienda Ospedaliero Universitaria Pisana

Pisa, Italy

D. Saulites Kandevicas Private Practice in Cardiology and Rheumatology | Liepaja, Latvia

Liepāja, Latvia

ORTO Clinic | Rheumatology Department

Riga, Latvia

Centro de Investigacion en Artritis y Osteoporosis S.C. (CIAO)

Mexicali, Estado de Baja California, Mexico

iBiomed Guadalajara

Zapopan, Guadalajara, Mexico

Centro Integral en Reumatologia, S.A. de C.V.

Guadalajara, Jalisco, Mexico

Private Practice - Dr. Delfina Villanueva Quintero

Guadalajara, Jalisco, Mexico

Consultorio de Reumatologia

Gustavo Adolfo Madero, Mexico City, Mexico

HMG Hospital Coyoacan

Mexico City, Mexico City, Mexico

CINTRE, Centro de Investigacion y Tratamiento Reumatologico S.C.

Mexico City, Mexico City, Mexico

Kohler and Milstein Research Yucatan

Mérida, Yucatán, Mexico

Hospitales Star Medica

Mérida, Yucatán, Mexico

Office of Cesar F. Pacheco-Tena, MD

Chihuahua City, Mexico

CGM Research Trust

Christchurch Central, Christchurch, New Zealand

Aotearoa Clinical Trials

Auckland, North Island, New Zealand

North Shore Hospital

Auckland, North Island, New Zealand

Porter Rheumatology Ltd

Nelson, South Island, New Zealand

Waikato Hospital

Hamilton, Waikato Region, New Zealand

Pratia Poznań

Poznan, Greater Poland Voivodeship, Poland

Centrum Medyczne Plejady

Krakow, Lesser Poland Voivodeship, Poland

Pratia MCM Krakow

Krakow, Lesser Poland Voivodeship, Poland

Krakowskie Centrum Medyczne

Krakow, Lesser Poland Voivodeship, Poland

Centrum Medyczne Katowice - PRATIA

Katowice, Lower Silesian Voivodeship, Poland

RCMed | Sochaczew, Poland

Sochaczew, Masovian Voivodeship, Poland

Rheuma Medicus | Warsaw, Poland