Clinical Research Directory

Inclusion Criteria: * Male or female subjects aged 18 years and older * Diagnosis of plaque psoriasis for at least 6 months * Eligible for phototherapy or systemic therapy * Plaque covering ≥ 10% of BSA * PASI ≥ 12, sPGA ≥3 Exclusion Criteria: * Diagnosis of non-plaque psoriasis or drug-induced psoriasis * Recent history of infection, history or risk of serious infection * Any major illness or evidence of unstable condition of major organ systems including psychiatric disease * Any condition possibly affecting the PK process of the study drug * Evidence of other skin conditions that would interfere with the evaluation of psoriasis * History of hypersensitivity to the ingredients of study drugs, history of anaphylaxis * Prior exposure to TYK2 inhibitors * Have received the prohibited treatment during the protocol required washout period * Any significant laboratory or procedure abnormalities that might place the subject at unacceptable risk during this study period