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RECRUITING
NCT06672523
PHASE1

A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion

Sponsor: Bristol-Myers Squibb

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the mass balance, metabolism, elimination, and drug levels of \[14C\]-BMS-986504 (MRTX1719) in participants with advanced solid tumors with homozygous methylthioadenosine phosphorylase deletion.

Official title: A Phase 1 Study to Evaluate the Mass Balance, Metabolism, Excretion, and Pharmacokinetics of [14C]-BMS-986504 (MRTX1719) in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

8

Start Date

2025-03-24

Completion Date

2026-04-20

Last Updated

2026-04-09

Healthy Volunteers

No

Interventions

DRUG

BMS-986504

Specified dose on specified days

DRUG

[14C]-BMS-986504

Specified dose on specified days

Locations (3)

ICON / PRA Magyarország Kft. Fázis I-es Klinikai Farmakológiai Vizsgálóhely

Budapest, Hungary

START Rioja, The START Center for cancer research

Logroño, Spain

Centro Integral Oncologico Clara Campal-Hospital HM Universitario Sanchinarro-START Madrid,

Madrid, Spain