Clinical Research Directory

INCLUSION CRITERIA: * ≥ 7 years old AND * Weight\>15Kg AND * The patient and/or where relevant their parent/guardian/caretaker/LAR willing and able to give informed consent /assent for participation in the study AND * Acute (duration ≤14 days) fever (37.5°C or higher or a history of fever in the previous 24h) For study group • Eschar OR Positivity to any of the screening tests (Immunochromatographic RDT or iiPCR) For negative control • Negativity to all screening tests (ten patients per hospital) EXCLUSION CRITERIA: * Other clear focus of infection (e.g. lobar pneumonia by chest x-ray, abscess) OR * Other clear cause of fever (e.g. positive Dengue IgM or NS1 antigen, positive blood cultures, untreated HIV)