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A Novel Strategy of ECMO Management Using Nafamostat for Regional Combined With Low Intensity Systematic Anticoagulation
Sponsor: Beijing Chao Yang Hospital
Summary
ECMO is widely used in patients with refractory respiratory and/or circulatory failure.The data shows that the incidence of bleeding and thrombotic events is still above 40%,and it is closely related to the increase in mortality rate.Therefore, optimizing ECMO anticoagulation management to reduce bleeding and thrombotic events is a key scientific issue that urgently needs to be addressed.
Official title: A Novel Strategy Combined Regional Anticoagulation in Membrane Oxygenator and Low-intensity of Systemic Anticoagulation Applied in Management of Extracorporeal Membrane Oxygenation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-11-01
Completion Date
2027-12-31
Last Updated
2024-11-18
Healthy Volunteers
No
Conditions
Interventions
Nafamostat
Nafamostat combined with unfractionated heparin for anticoagulation
Heparin
unfractionated heparin for anticoagulation
Locations (1)
Bing Sun
Beijing, Beijing Municipality, China