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NOT YET RECRUITING
NCT06676475
PHASE2/PHASE3

Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle

Sponsor: Misr University for Science and Technology

View on ClinicalTrials.gov

Summary

The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years old with myofascial pain with masseter muscle trigger points. The main questions it aims to answer are: * which treatment has longer effect of pain release with the least possible side effects and recurrence rate? * Which treatment has greater impact on improving patient's quality of life? Researchers will compare Botulinum toxin type A, magnesium sulfate to a placebo saline injections in treatment of the masseter muscle trigger points Participants will attend to the clinic 4 times * 1st visit will include taking preoperative records and treatment injection * 2nd visit will be follow up and taking records after 1 month * 3rd visit will be follow up and taking records after 3 months * 4th visit will be follow up and taking records after 6 months

Official title: Comparison of the Effectiveness of Botulinum Toxin and Magnesium Sulfate Injections in the Treatment of Myofascial Trigger Points in the Masseter Muscle Randomized Controlled Clinical Trial

Key Details

Gender

All

Age Range

16 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2024-12-01

Completion Date

2025-08

Last Updated

2024-11-12

Healthy Volunteers

No

Interventions

DRUG

MgSO4

2ml MgSo4 (Magnesium sulfate sterile ampoule 10 ml, 100 mg/ml = 0.41 mMol/ml. Egyptian Int. Pharmaceutical Industries Co., Egypt).

DRUG

BOTOX-A

2ml of BTX

DRUG

Saline (NaCl 0,9 %) (placebo)

2 ml of saline

Locations (1)

Misr university for science and technology

Giza, Egypt