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Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
Sponsor: Misr University for Science and Technology
Summary
The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years old with myofascial pain with masseter muscle trigger points. The main questions it aims to answer are: * which treatment has longer effect of pain release with the least possible side effects and recurrence rate? * Which treatment has greater impact on improving patient's quality of life? Researchers will compare Botulinum toxin type A, magnesium sulfate to a placebo saline injections in treatment of the masseter muscle trigger points Participants will attend to the clinic 4 times * 1st visit will include taking preoperative records and treatment injection * 2nd visit will be follow up and taking records after 1 month * 3rd visit will be follow up and taking records after 3 months * 4th visit will be follow up and taking records after 6 months
Official title: Comparison of the Effectiveness of Botulinum Toxin and Magnesium Sulfate Injections in the Treatment of Myofascial Trigger Points in the Masseter Muscle Randomized Controlled Clinical Trial
Key Details
Gender
All
Age Range
16 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-12-01
Completion Date
2025-08
Last Updated
2024-11-12
Healthy Volunteers
No
Conditions
Interventions
MgSO4
2ml MgSo4 (Magnesium sulfate sterile ampoule 10 ml, 100 mg/ml = 0.41 mMol/ml. Egyptian Int. Pharmaceutical Industries Co., Egypt).
BOTOX-A
2ml of BTX
Saline (NaCl 0,9 %) (placebo)
2 ml of saline
Locations (1)
Misr university for science and technology
Giza, Egypt