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Skeletal Muscle Myokine Response to Acute Eccentric Exercise
Sponsor: University of Manitoba
Summary
The purpose of this study is to evaluate the acute local skeletal muscle inflammatory response to thigh muscle (quadriceps) eccentric muscle actions. Eccentric muscle actions occur when the muscle is lengthening as it contracts. This is a pilot project to assess the degree of inflammatory biomarkers, called myokines, that are released locally in skeletal muscle tissue after an acute bout of resistance-exercise using a resistance-exercise machine called an isokinetic dynamometer.
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2024-11-15
Completion Date
2025-11-01
Last Updated
2024-11-07
Healthy Volunteers
Yes
Conditions
Interventions
Eccentric resistance-exercise
Each participant will complete 300 repetitions of eccentric knee extensions using an isokinetic dynamometer after a baseline skeletal muscle biopsy is taken. Three hours following this, a second muscle biopsy will be taken to evaluate the changes in the dependent variables being measured (myokines).
Locations (1)
Applied Research Centre, Faculty of Kinesiology, University of Manitoba
Winnipeg, Manitoba, Canada