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A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
Sponsor: Recursion Pharmaceuticals Inc.
Summary
This is a multi-center, open-label study to investigate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary activity of REC-1245 administered orally on a once daily (QD) schedule in participants with unresectable, locally advanced, or metastatic solid tumors.
Official title: A Phase 1 / 2, Open-Label Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
85
Start Date
2024-11-21
Completion Date
2028-10-30
Last Updated
2025-12-05
Healthy Volunteers
No
Interventions
REC-1245
Oral
Locations (6)
City of Hope
Duarte, California, United States
Cleveland Clinic
Cleveland, Ohio, United States
SCRI Oncology Partners - PPDS
Nashville, Tennessee, United States
START Mountain Region
West Valley City, Utah, United States
McGill University Health Centre (MUHC) - The Montreal
Québec, Canada, Canada
Princess Margaret Cancer Centre
Toronto, Ontario, Canada